Normal
Mouse
Average systolic pressure = 125 mmHg
Average diastolic pressure = 90 mmHg
Average mean pressure = 111 mmHg
Heart rate = 580 beats per minute
Average systolic pressure = 121 mmHg
Average diastolic pressure = 90 mmHg
Average mean pressure = 107 mmHg
Heart rate = 600 beats per minute
Leptin has
numerous signaling pathways in the brain. One such pathway is through
a neurotransmitter called alpha melanocyte stimulating hormone. When leptin
levels rise, alpha MSH rises. If given to an animal, alpha MSH causes
metabolic rate to rise and causes satiety (lack of hunger). A naturally
occuring mutation blocks the function of alpha MSH. These mice, termed
agouti for their yellow coat color, are obese, but not to the extent of
the mice missing leptin.
(The
code for the applets is heavily based on the Graph Package created by
Leigh Brookshaw(c)1996 used under the terms of the GNU General Public
License).
